Cancer

A recent study investigated whether chemoradiotherapy or radiotherapy alone would be effective for women diagnosed with high-risk endometrial cancer. Endometrial cancer, also known as uterine cancer, is a type of cancer that begins in the endometrium, which is the lining of the uterus. Since the first sign of endometrial cancer is abnormal vaginal bleeding when
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A recent review in Science outlines the intricate relationships between the gut microbiome and our responsiveness to cancer immunotherapy. All mammals including humans are endowed with a flourishing community of microorganisms within their gut. Humans, for instance, have an average of 30 trillion bacteria thriving within our gut; this bacterial community is called the microbiome.
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A recent review article published in Science summarizes the successes and drawbacks of a novel immunotherapy using CAR T cells to treat cancer. The immune system plays an important role in detecting and eliminating cancer cells in our body. The most notable type of immune cell responsible for targeting cancer cells are known as effector
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A recent article examines a new immunotherapy strategy that slowly releases immune-activating molecules at the tumor resection site to prevent disease relapse and metastasis. Cancers are notoriously difficult to treat, as they are comprised of transformed cells that grow in an uncontrolled manner. In particular, the surgical resection of tumors can actually promote wound healing,
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Since treatment options for patients with advanced urothelial carcinoma are limited, researchers are investigating the effectiveness of Atezolizumab. Urothelial carcinoma is the most common type of cancer affecting the urinary system. In its advanced stage, rates of survival are low, with few patients surviving longer than five years.  Platinum-based chemotherapy is the standard first-line treatment,
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A creative meta-analysis published in PLOS Medicine has weighed overall risk vs. benefit in pediatric cancer clinical trials. The Canadian Cancer Society documents that cancer causes more fatalities in children than asthma, diabetes, cystic fibrosis, and AIDS combined. Pharmaceutical companies and the global scientific community work tirelessly to reduce the mortality due to pediatric cancer.
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A study conducted on a Danish population of breast cancer patients investigates the impact of expressive writing for improved physical outcomes. Emotional expression is essential to physical well-being. While the evidence is mixed, some research indicates that repressive coping and emotional avoidance leads to the development of and a poor outcome for breast cancer. There
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A ground-breaking research study has shown the utility of lab-grown pieces of gastrointestinal cancer in predicting outcomes in on-going clinical trials. Pharmaceutical companies worldwide spend billions of dollars on pre-clinical and clinical trials. Unfortunately, despite careful and painstaking research conducted at the preclinical level, the vast majority of pre-clinical leads are abandoned at some stage
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A recent study in The British Medical Journal has evaluated the impact of eight leading chronic diseases and physical activity on cancer risk. Most of us dread the question: how much cancer risk do we carry given our disease history and current lifestyle? While there has been no single definitive answer to this question, there have been numerous epidemiological
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Ovarian cancer is one of the most common causes of gynecological cancer-related deaths in women. A recent study in the Netherlands evaluated whether the standard treatment or intraperitoneal chemotherapy for ovarian cancer is the favourable treatment option.   Ovarian cancer has one of the highest mortality rates of all gynecological cancers in the western world
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Researchers in the US investigated whether diet-induced inflammation plays a key role in the development of colorectal cancer. Worldwide, colorectal cancer is the third most common cancer afflicting humans. This cancer targets older men and other lifestyle risk factors include diet, obesity, smoking, and physical activity level. This disease is primarily diagnosed using endoscopic analysis,
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In a recent study, researchers developed a series of cell lines that may form the basis of a drug screen platform for breast cancer using organoids.   Applying breast cancer therapies that are appropriate for a specific tumour’s composition, behaviour, and the specific mechanisms which allow it to grow, spread, and survive remains a challenge.
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